- THE IN VITRO IMPACTS OF SOME PLANT EXTRACTS ON CARBONIC ANHYDRASE I, II AND PARAOXONASE-1 - Article Sidebar pdf Published Mar 22, 2019 Main Article Content Şükrü Beydemir Anadolu University Abstract The presented article focuses on the in vitro inhibition of plant extracts on the human carbonic anhydrase (CA) isoforms hCA I, hCA II, and paraoxonase-1 (PON1) activities. Five different plants (Alcea rosea, Foeniculum vulgare, Elettaria cardamomum, Laurus azorica and Lavandula stoechas) were selected in this study. methanol, ethanol, and water extracts of plants were prepared and the concentration-dependent inhibition degrees were found for CA I and II isozymes and PON1 spectrophotometrically. Thus, IC50 (mg/mL) values were obtained for each extract. Methanolic extract of Elettaria cardamomum has the highest inhibitory effects (0.032 mg/mL). The water extracts of plants showed lower inhibitory impacts compared to the methanol and ethanol extracts. Article Details How to Cite BEYDEMIR, Şükrü. - THE IN VITRO IMPACTS OF SOME PLANT EXTRACTS ON CARBONIC ANHYDRASE I, II AND PARAOXONASE-1. Hacettepe Journal of Biology and Chemistry, [S.l.], v. 47, n. 1, p. 51-59, mar. 2019. ISSN 1303-5002. Available at: <http://hjbc.hacettepe.edu.tr/index.php/hjbc/article/view/173>. Date accessed: 23 jan. 2021. ABNT APA BibTeX CBE EndNote - EndNote format (Macintosh & Windows) MLA ProCite - RIS format (Macintosh & Windows) RefWorks Reference Manager - RIS format (Windows only) Turabian Issue Vol 47 No 1 (2019): HJBC 47 Section Articles